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The 1,4-Dioxane Book

The Complete Reference
Chapters 9 and 10 – Table of Contents
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Chapter 9       Forensic Applications for 1,4-Dioxane and Solvent Stabilizers
9.1 Leveraging 1,4-Dioxane Data for Plume Analysis and Source Apportionment
9.1.1 Estimating the Mass of the Release
9.1.2 Impurities
9.2 Ratio Analysis
9.2.1 Ratio Analysis of Methyl Chloroform Breakdown Using 1,4-Dioxane
9.2.2 Using Ratios to Approximate the Date of a Release
9.2.3 Modeling 1,4-Dioxane Migration to Approximate the Date of a Release
9.2.4 Compound-Specific Isotope Analysis
9.2.5 Compound-Specific Isotope Analysis of 1,4-Dioxane Biodegradation
9.3 Solvent Stabilizers as Age Markers
9.4 Solvent Stabilizers as Markers of Solvent Applications
9.4.1 Perchloroethylene as a Dielectric Fluid

Chapter 10       Regulatory Policy Implications of 1,4-Dioxane
10.1 Applying the Precautionary Principle to Regulation of 1,4-Dioxane and Emerging Contaminants in Drinking Water
10.1.1 Emerging and Unregulated Contaminants
10.2 1,4-Dioxane and drinking water policy
10.2.1 1,4-Dioxane Detections and Drinking Water Testing Program Policy
10.2.2 US EPA’s Contaminant Candidate List Includes 1,4-Dioxane
10.2.3 Integrating Awareness of Groundwater Cleanups to Prioritize 1,4-Dioxane Monitoring in Water Supply
           Well Sampling Programs
10.2.4 Predicting Water Supply Well Contamination
10.2.5 Moving Beyond Checklist Compliance
10.3 Updating the Toxicological Basis for 1,4-Dioxane Regulation
10.3.1 Addressing Synergistic Effects of Multiple Contaminants
10.3.2 The Promise of Cell Lines to Accelerate and Improve Toxicology Assays
10.3.3 Applying Computational Toxicology to Physiologically-Based Pharmaco-Kinetic Modeling
10.4 Regulatory Policy on 1,4-Dioxane Remediation at Cleanup Sites
10.4.1 Monitored Natural Attenuation and 1,4-Dioxane
10.4.2 1,4-Dioxane and NPDES Effluent Limitations
10.4.3 Lessons Learned from 1,4-Dioxane Case Studies
10.4.4 1,4-Dioxane Treatment Technology Research Needs
10.5 Blindsided Again?
10.6 The Promise of Green Chemistry
10.7 Should 1,4-Dioxane be Banned?
10.8 Regulatory Policy Recommendations for Addressing 1,4-Dioxane Releases

Appendix 1: Synopses of Selected Patents from the Art of Solvent Stabilization
Appendix 2: Fate and Transport Properties of Solvent-Stabilizer Compounds
Appendix 3: Compilation of Instrumental Parameters in Literature Studies of 1,4-Dioxane Analyses of Various Media

Index .................................................................................................................................................................................505